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Pullulan is mainly used by the cell to resist desiccation and predation.

Pullulan is a polysaccharide consisting of repeating units of maltotriose residues. It is produced from starch by the yeast-like fungus Aureobasidium pullulans. Pullalan has been used as a carrier for oral, nasal and lung transmucosal drug delivery systems.

Chemical compound

Pullulan is a polysaccharide polymer consisting of maltotriose units, also known as α-1,4-;α-1,6-glucan'. Three glucose units in maltotriose are connected by an α-1,4 glycosidic bond, whereas consecutive maltotriose units are connected to each other by an α-1,6 glycosidic bond.

Pullulan is an extracellular glucan prepared by fermentation by the fungal strain Aureobasidium pullulans generally referred to as “black yeast” [72, 86]. Pullulan is a stable compound, which forms a viscous solution when dissolved in cold or hot water, but the gel does not form. It does not dissolve in any organic solvent except for dimethylformamide and dimethyl sulfoxide [87, 88]. A characteristic feature of pullulan is that it is a tasteless, odorless white powder. The solution of pullulan is stable over a wide range of pH values and it is heat resistant [89, 90]. Pullulan is used as a binder, thickener (0.2%–3%), and coating agent in food.

Pullulan from Aureobasidium pullulans (CAS 9057-02-7)

Solubility in water: Soluble

Formula: (C6H12O5)n

Appearance: White powder

ECHA InfoCard: 100.029.938

An Introduction to Green Nanotechnology

Mahmoud Nasrollahzadeh, ... Zahra Issaabadi, in Interface Science and Technology, 2019

5.4.2.5 Pullulan

Polysaccharides in food industry

Mahmoud Nasrollahzadeh, ... Fahimeh Soleimani, in Biopolymer-Based Metal Nanoparticle Chemistry for Sustainable Applications, 2021

2.6.3 Pullulan